N-methylamphetamine (also known as methamphetamine or meth) is a potent central nervous system stimulant discovered in 1893 by Japanese chemist Nagai Nagayoshi. Meth generally refers to a racemic mixture of L-methamphetamine and D-methamphetamine. Both component...
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Gold-Conjugated Antibodies

Antibodies, also called immunoglobulins, are Y-shaped proteins produced by an immune system to identify specific antigens. Often these antigens are pathogens such as viruses or bacteria which, when recognized by and bound to a corresponding...
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What is Delta-9-THC-BSA?

Delta-9-THC-BSA is a drug-protein conjugate synthesized by binding the animal protein bovine serum albumin (BSA) to cannabinoid delta-9-tetrahydrocannabinol (delta-9-THC). The cannabinoid was first isolated in 1964 and has subsequently been identified as the primary active...
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Outlining THC-BSA

Tetrahydrocannabinol (THC) is the primary psychoactive compound in the cannabis plant. It can be detected and quantified in biological samples with relative ease, using a conjugation of THC molecules covalently bound to the animal protein...
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Outlining Chloramphenicol Conjugates

Chloramphenicol conjugates are comprised of small molecule chloramphenicol that is covalently bound to the protein bovine serum albumin (BSA). Typically, chloramphenicol conjugates are synthesized for competitive or direct enzyme-linked immunosorbent assay (ELISA) analysis, where the...
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What are Gabapentin Conjugates?

Gabapentin conjugates are compounds of the anticonvulsant drug, marketed primarily as Neurontin, and the animal protein bovine serum albumin (BSA). They are broadly used for enzyme-linked immunosorbent assay (ELISA) or lateral flow immunoassay detection of...
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Outlining Ketamine Conjugates

Ketamine is a selective antagonist of the N-methyl-D-aspartate (NMDA) receptor in the central nervous system, which blocks the flow of excessive ions through the receptor’s channel to prevent overactivation and resultant excitotoxicity. This has fuelled...
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How Accurate are Rapid Drug Tests?

Rapid drug tests commonly refer to in-house drug screening paraphernalia that has become increasingly popular in recent years, with growing numbers of employers adopting toxicology screening processes during hiring and reviewing procedures. These are primarily...
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The History of Immunochemistry

Immunochemistry is an area of biochemical research and production that is chiefly concerned with immunological responses and biomolecular mechanics. Its underlying aim is to improve global understandings of antibodies and antigens, and the interplay between the two.

What is a Protein Drug Conjugate?

Drug conjugates or hapten conjugates are highly-targeted chemical compounds covalently bound to a protein such as BSA, BTG and/or enzymes such as HRP. These compounds are used in a range of academic pharmaceutical and diagnostic applications.

The Rising Superbugs

By: Francisco J. Rojas, Ph.D.   A recent survey indicates that only half of Americans know that antibiotics kill bacteria but not viruses. The finding is in line with studies showing that one in four Americans...
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Kratom and its Alkaloids

March 2017 Francisco J. Rojas, Ph.D. In August 2016, the US Drug Enforcement Administration (DEA) announced plans to designate mitragynine and 7-hydroxymitragynine, two alkaloid compounds that naturally occur in the leaves of kratom, as a...
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Cannabinoid receptor structure revealed

By: Francisco J. Rojas, Ph.D.  Marijuana, the cannabis plant, is a psychoactive (mind-altering) drug that contains compounds called cannabinoids. The plant’s primary drug effects come from the chemical delta-9-tetrahydrocannabinol, or THC. Individual cannabinoid chemicals may...
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Proposition 64

Being a California-based company, Pyxis is continuing to focus this month on the legal status of marijuana.  On November 8, California voters will be asked to consider Prop 64, which effectually legalizes the use of...
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Marijuana Legalization

We have been carefully watching the cultural and political implications of the increasing legalization of marijuana.  Like anything else, it seems to be a matter of striking a comfortable balance between the needs of everyday...
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Welcome to our new blog!

We are very excited to introduce Pyxis’ blog, where you will find educational information regarding drug conjugates, antibodies, rapid drug test, and broader industry interests; read about the latest innovations in our field; and be...
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Sem Porta Mollis Parturi

Lorem ipsum dolor sit amet, consectetur adipisici elit, sed eiusmod tempor incidunt ut labore et dolore magna aliqua. Idque Caesaris facere voluntate liceret: sese habere. Magna pars studiorum, prodita quaerimus. Magna pars studiorum, prodita quaerimus....
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